Royal Air Force Typhoon fighter aircraft have operated alongside France's air force in a coordinated attack on an hidden munitions depot in Syria operated by the IS group, per a report from the British defence ministry.
The site, located using surveillance, was thought to be containing munitions and bombs, the statement said, and was located in mountainous terrain just to the north of the historic site of Palmyra in the heart of Syria.
"Our fighter planes employed precision-guided Paveway IV munitions to target a several access tunnels down to the facility... early reports indicate the target was engaged successfully," the MoD said.
There was no indication of any civilian impact in the attack on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
IS - alternatively referred to as Daesh - imposed militant control over parts of both Syria and Iraq until 2019.
"This strike demonstrates our UK leadership, and resolve to stand shoulder to shoulder with our allies, to eradicate any re-emergence of the terrorist group and their dangerous and violent ideologies in the region," the British Defence Secretary the Defence Secretary remarked.
RAF aircraft have performed surveillance missions over Syrian airspace to "forestall any attempted comeback" of the group following its routing at the Baghuz confrontation in 2019, the authorities noted.
"I must thank all the members of the UK armed forces involved in this strike for their expertise and their valour," Healey added. "They were among thousands of UK service members on duty over the festive period. This mission, to eliminate dangerous terrorists who endanger our safety, shows how our armed forces are always on standby, all year round, ensuring Britain's security domestically and influential overseas."
In December, the US military executed what it called a "large-scale strike" against IS targets in Syria, following an attack resulted in the deaths of two US servicemembers and a local interpreter in Palmyra.
The UN estimates IS still has roughly 5-7 thousand militants in both countries.